Us study: Vape use during teen pregnancy increased by 3.3% from 2016 to 2021

According to a study published online by “JAMANetworkOpen” on December 13, during teen pregnancy in the United States, the use of vapes in the third trimester increased from 0.8 percent in 2016 to 4.1 percent in 2021.

The researchers analyzed data from the Pregnancy Risk Assessment Surveillance System from 2016-2021, focusing on 10,428 adolescents aged 10-19 who had already given birth to single births and provided information about their use of e-cigarettes or tobacco.

While the researchers found a roughly five-fold increase in e-cigarette use alone, the proportion of pregnant women who used tobacco only dropped from 9.2 percent in 2017 to 3.2 percent in 2021. Between 0.6% and 1.6%, the proportion of pregnant women using vapes and tobacco together fluctuated.

There was no significant difference in the proportion of teens with low birth weight who did not smoke or use e-cigarettes (12.9 percent) and those who only used vapes (16.8 percent) or used tobacco and e-cigarettes together (17.6 percent). The researchers found that smoking was significantly associated with a lower birth weight (24.6 percent).


The corresponding author of the study, XiaozhongWen of the Zetz School of Biomedical Sciences and Medicine at the State University of New York at Buffalo, said:

“In our analysis, there did not appear to be a statistically significant association between exclusive use of  vapes and tobacco and e-cigarettes with lower birth weight, but given the low prevalence and limited sample size, this finding should be interpreted with caution.”


A limitation of the study is that participants may have reported their use of vapes and tobacco because they feared social humiliation. In addition, the researchers lacked information on e-cigarette use, exposure to secondhand smoke, marijuana use, and dietary habits during first and second pregnancies.

The study was supported by the National Institute on Drug Abuse, the Food and Drug Administration’s Cigarette Products Display, the Chinese Heart, Lung, and Blood Institute, and the American Heart Association. One of the discovery partners received donations from Pfizer and personal fees during Johnson & Johnson, the World Health Organization, and the Campaign for a Tobacco-Free Childhood.